Microbiology and Immunology 2500A/B Study Guide - Final Guide: Antibody, Blood Test, Diplococcus
10 Sep 2020
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Bubonic plague: swollen lymph nodes (groin, neck, armpits) bubous; develops into septicemic plague pneumonic. 1: biofilm (fleas, lps (sepsis, phospholipase (survival in flea, plasminogen activator: bursts blood clots spread of pathogen, yersiniabactin: recruits fe, type iii secretion: Enteritis (humans): inflammation of small intestines, diarrhea pyv virulence plasmid (-) rod, cre , capsule klebsiella pneumoniae ha-pneumonia: difficile. Gi inflammation with super stinky diarrhea, abdominal pain, fever, nausea, dehydration. Diagnosed by yellow lesions (forms a pseudomembrane over mucosa) A" subunit ( a ctive) = enzyme that inactivates regulatory proteins cytoskeletal rearrangement, cell death, inflammation damaged gi lining. B" subunit ( b inding) = binds to host cell surface receptors for uptake: botulinum, tetani, perfringens. Abx: oral vancomycin, iv metronidazole, fecal microbiota transplant. Tx: discontinue other abx, fluids, avoid antidiarrheal agents (decreases toxic clearance) 2 dic (disseminated intravascular coagulation) : widespread blood-clotting, depletion of clotting factors; caused by cytokine storm. 3 bacteremia: presence of bacteria in blood; sometimes asymptomatic, can lead to sepsis.
