Microbiology and Immunology 2500A/B Study Guide - Final Guide: Coccobacillus, Enterococcus, Fetus

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19th century - all around the world, active until 1959, 25 mil europeans died. Has an intra and extra phase (in macrophage vs in blood stream) Survives and grows in innate immune cells (macrophages) Kills phagocytes and continues to grow extracellularly. At the terminal stages of the disease, your blood has lots of bacteria so the fleas can pick it up. Handling infected animals or ingesting infected meats. Transmission via aerosols directly into the lungs, or spread to lungs from septicemic plague. Swollen lymph nodes in groin, armpits and neck. Culture and then identify from buboes, sputum or blood. Enterococci (vre: faecalis - more virulent but less drug resistant, faecium - less virulent but more drug resistant. Vre - vancomycin resistant, no longer just colonizers. Globally disseminated, have resistance to van genes. Produces a capsule and is commonly resistant to multiple antibiotics beta lactamase resistant beta lactams with broad spectrum activity. Can cause life threatening diseases mediated by exotoxins.