Microbiology and Immunology 2500A/B Study Guide - Final Guide: Aspergillus Fumigatus, Cryptococcus Gattii, Cryptococcus Neoformans

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Inhaling spores from soil contaminated heavily with bird or bat dropping. Pets get it from snif ng around so much. San joaquin valley fever (er visits on rise with windstorms in. Only one not transmitted by inhalation (must be pricked) Satellite lesion on skin away from affected body entrance. Diaper rash, balanitis, nails/ paronychia, mucous membrans (thrush/ vaginitis), uti. Immunocompromised: aspergilloma fungus ball in pulmonary cavity. Fumigatus: allergic bronchopulmonary fx in asthmatics and cf pts. Avus: infect peanuts and corn producing a atoxin --> liver cancer. Ulceration from little toe on (least mycolic acid secretion) Starts to heal from the middle but scaling on outside remains. Called a kerion when the lesion is on the scalp. Dis gurating infection requiring lots of drug therapy and reconstructive surgery. More in immunocompromised pts: starts with sinusitis. Initial pulmonary infection that can disseminate to skin, bone and genitourinary tract. Skin dissemination looks like cancer on the nose but the septum is still there.