Physiology 1021 Study Guide - Final Guide: Hyperthyroidism, Enteric Nervous System, Follicular Phase

• School: Western University
• Department: Physiology
• Course: Physiology 1021
• Professor: Prof

Document Summary

Specificity of receptors only cells with a receptor that recognizes the chemical messenger will respond receptors are proteins given receptor only binds to one type or a limited number of molecules with a similar 3-d structure. Location of receptors receptor in cytosol receptor in nucleus. Membrane bound receptors ion channels function as an enzyme, insulin: activate a cytoplasmic protein, stimulates reaction, activate a membrane-bound g protein, gtp instead of atp turns on certain enzymes in the cell lipophillic and lipophobic signal molecules. Terminology regulation of receptors: up regulation- increase in number of receptors in response to low exposure to signal, down regulation- decrease in the number of receptors in response to high exposure to signal. Local cell communication neurotransmitter -> receptor -> autocrine( cell secretes signal and has receptor for that signal) and paracrine (signal diffuses to neighbouring cells) signals. Endocrine- chemical secreted into blood stream, effects distant cells.