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Dopamine, Neurotransmitters & Nervous System These notes include everything that Prof Birot talked about on Nov 24. It includes Dopamine, Amino Acid Neurotransmitters, Neuropeptides, Notion of Convergence and Divergence, Organization of Nervous System (Af

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York University
Kinesiology & Health Science
KINE 2011
Gillian Wu

24/11/2010, 9:33 AM Dopamine  Cocaine inhibits its reuptake by competing with the transporter in charge of this reuptake process  Dopamine continues to activate certain neurons among them  This plays a role in emotional responses, especially feelings of pleasure Amino Acid Neurotransmitters GABA (gamma-aminobutyric acid)  Major inhibitory neurotransmitter in the brain  Benzodiazepine drugs (Xanax, Valium) increases chloride flux through GABA receptor  This reduces anxiety, protect against seizures, help to sleep Tetanus toxin - prevents the release of GABA from presynaptic element; consequences?  No inhibition  Intense muscle contraction (could break your bones)  Can lead to fatality (500 000 people die a year) Neuropeptides  Small size  Trigger the opening of channels in a few msec  Synthesized in the presynaptic region and packaged in synaptic vesicles Neuropeptides:  Synthesized in cell body  Larger molecules Notion of Convergence and Divergence Screen clipping taken: 24/11/2010, 9:46 AM ORGANIZATION OF THE NERVOUS SYSTEM Screen clipping taken: 24/11/2010, 9:46 AM THERE IS NO NERVE IN THE CENTRAL NERVOUS SYSTEM  Such group of axons is named pathway or tract or commissure when it links the right and the left halves of the brain  Ie. hand on oven burner - central nervous system says "it's hot, it's painfu
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