EXSC 530 Study Guide - Midterm Guide: Glycogen Phosphorylase, Pyruvate Dehydrogenase, Glycogen Synthase
18 Feb 2018
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In aerobic system, nadh is shuttled to the mitochondria for atp generation. 1 pyruvate 1 nadh and 1 acetyl-coa: 1 turn of krebs: Krebs cycle intermediates: products of beta-oxidation, 1 nadh, 1 fadh, 1 acetyl-coa, modulators of rate-limiting enzymes, levels of atp and adp+pi, high levels atp inhibit atp production, calcium. Increased levels directly stimulate enzymes like phosphorylase, which catalyzes glycogenolysis: stimulant- increases rate of krebs cycle, ph. Increase in acidity slows enzyme activity: drop in ph inhibits pfk, citrate, first product of step 1 in krebs cycle. Isometric contraction: muscle exerts force, but doesn"t change length: ie. Postural muscles: dynamic (isotonic) contraction: can be concentric or eccentric; muscles change length, concentric action: muscles shorten as they produce force, eccentric action: muscles produce force, but length increases, associated with muscle injury/soreness, ie. Running downhill: a muscle twitch is contraction as a result of a single stimulus, the latent period lasts about 5ms, contraction lasts about 40ms, and relaxation lasts about.
