END 319 Study Guide - Midterm Guide: Pseudoautosomal Region, Heterozygote Advantage, Dosage Compensation

25 views2 pages

cyanmink520

3 Jun 2019

School

University at Buffalo

Department

Environmental Design

Course

END 319

Professor

all

For unlimited access to Study Guides, a Grade+ subscription is required.

Document Summary

When heterozygotes express intermediate phenotype when heterozygotes somehow display recessive when the alleles of one phenotype mask the phenotypic effect of the. What is incomplete dominance? instead of dominant phenotype. What is epistasis? alleles of the other type. What is complementation? when phenotypic recessive parents (with epistasis) produce wild- type phenotypic offspring. What is gene redundancy? one gene can compensate for the loss of function of another gene. What"s the difference between pleiotropy and polygenic? pleiotropy = one gene affects multiple traits polygenic = multiple genes affect one trait. What is haploinsufficiency? mutant allele is loss of function normal allele can"t produce enough heterozygote has disease. What is a dominant-negative mutation? antagonistically to the normal protein it counteracts the normal protein and alters the phenotype. What is another term for over dominance? heterozygote advantage. What is the gene modifier effect? alleles of one gene are modified by alleles of another gene instead of masked.

Related Questions

QUESTION 1

Jim is blood type A, his brother John is type O and his sister Jane is type AB. What are the genotypes of their parents?

Which of the following is true for alleles that show incomplete dominance?

Heterozygotes have a genotype like the dominant allele.

Homozygotes have a genotype like the recessive allele.

Heterozygotes have a phenotype intermediate between the dominant and recessive alleles.

Homozygotes have the same phenotype as the heterozygotes.

QUESTION 3

Which principle of inheritance concluded that when games are formed in meiosis, the two alleles of each gene separate from one another, and each gamete receives only one allele?

independent assortment

Which term best describes a condition in which alleles at one locus can alter the expression of alleles at another locus?

polygenic inheritance

A single unit of genetic information located on a chromosome defines:

The physical expression (appearance or function) of an organism's genes defines:

genotype

a single characteristic

Palomino horses (golden color with a blond mane) are an incompletely dominant trait produced by the combination of the chestnut color allele and the cream color allele. If you wanted to produce as many palominos as possible, which mating strategy below would be the best choice?

Which term best describes the effect of a single gene on multiple aspects of the phenotype?

polygenic inheritance

QUESTION 9

Which term best describes the separate expression of both alleles for a single trait in the same cell?

polygenic inheritance

QUESTION 10

One form of a gene found on a single chromosome defines:

A chocolate lab (whose mother was a yellow lab) is mated with a black lab whose genotype is BbEe. What fraction of the offspring would be expected to be yellow labs?

What type of allele is always expressed regardless of whether the individual is homozygous or heterozygous for it?

Both the dominant and recessive alleles

Given the parents AABBGgHhrr Ã AabbGgHhRr, assume simple dominance and independent assortment. What proportion of the progeny will be expected to have the genotype AaBbggHHrr?

___________________ is defined as having two of the same type of allele for a particular trait.

The physical position of an allele on a single chromosome defines:

Which term best describes two or more genes affecting the phenotype in an additive fashion?

codominance

polygenic inheritance

Differentiate amongcomplete dominance, incomplete dominance andco-dominance.

3. Understand an allelicseries -How many possible alleles are there for any given gene? Isthere only one recessive allele for a gene? Is there only onedominant allele for a gene? Is an allele always recessive ordominant with respect to other alleles of the gene?

4. What is a lethalallele? Are lethal alleles usually dominant or recessive? Are thereany exceptions? (Hint: Huntington disease in humans). How do wemaintain stocks with lethal alleles?

5. How can you tell if anallele is lethal? If one of the parents has a lethal allele, wouldall the possible genotypes be present in the progeny? What wouldhappen to the phenotypic ratios of the progeny?

6. What ispleiotropy?

7. How can you tell if atrait is determined by more than one gene? What ratios ofphenotypes in the F2 generation would you expect if a trait isdetermined by a single gene?

8. What is epistasis? Howcan the genotype at a locus affect the phenotype determined by thegenotype at another locus? What are complementary gene action,duplicate gene action, dominant suppression, dominant epistasis,and recessive epistasis?

skyrat774

Q.In the non-9:3:3:1 ratio dihybrid cross below, there are 3 classes of phenotypes: white, pink, red which of the following is NOT true?

9 A_B_ white

3 A_bb pink

3 aaB_ red

1 aabb red

a.) phenotype is dependent on the genotype of gene B

b.) This is an example of recessive episasis

c.) aa is epistatic to B_, and bb

d.) phenotype is dependent on the genotype of gene A

Q,When choosing a selectable marker, you...

a.) choose a enhancer for your gene of interest

b.) choose a rescue gene to save your gene of interest

c.) choose a resistant gene that will allow for colony screening

d.) choose a gene that encodes for DNA replication

Q.The following steps detail an experiment resulting in transgenic mice with a knockout gene for fur color. Recall that agouti (brown) mice are A/A;M/M and black fur coats are a/a;M/M . List the steps in their correct chronological order.

1.Inject transformed agouti embryotic cells into an a/a;M/M embryo to produce A/A;M/m and a/a;M/M altered embryo

2.Self-cross hemizygous mice to produce homozygous transgenic mice (A/-;M/m)

3.Create a a targeting vector containing tk+ for ganciclovir sensitivity, neoR for neomycin resistance, and the gene encoding fur color.

4.Observe mice with chimeric phenotype and cross them with black a/a;M/M mice to produce transgenic hemizygous progeny (A/a;M/m)

5.Isolate all transformed embryonic stem cells that show homologous recombination and inject them into a embryonic stem cells of an agouti mouse.

a.) 3,5,4,1,2

b.) 1,5,3,4,2

c.) 3,5,1,4,2

d.) 5,3,2,4,2

If dog 1 has is black with alleles (A_B_) , and dog 2 is brown with (aaB_), and dog 3 is yellow with (_ _bb) alleles, what kind of epistasis is this and what color would dog 4 be if he was (AAbb).

1. Recessive epistasis, Yellow

2. Recessive epistasis, Black

3. Dominant epistasis, Yellow

4. Dominant epistasis, Black

A gene interaction in which pair of recessive genes at one locus prevents expression of dominant allele at another locus called

a. incomplete dominance

b. epistatis

c. complete dominance

d. polygenic inheritance

END 319 Study Guide - Midterm Guide: Pseudoautosomal Region, Heterozygote Advantage, Dosage Compensation

Document Summary

Get access

Related Documents

END 319 Study Guide - Midterm Guide: Zygosity, Mendelian Inheritance, Meiosis

CAS BI 206 Chapter Notes - Chapter 3: Penetrance, Allele Frequency, Epistasis

BIO152H5 Study Guide - Midterm Guide: Quantitative Trait Locus, Antimicrobial Resistance, Aquatic Adaptation

Related Questions