BIO SCI 93 Study Guide - Midterm Guide: Ddb Worldwide, Hydrogen Bond, CentrosomeExam


Department
Biological Sciences
Course Code
BIO SCI 93
Professor
Jorge Busciglio Kim Green Marcelo A Wood
Study Guide
Midterm

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Bio 93 Exam 1
Practice Exam A Key
This is an old exam from Bio Sci 93. Use this to gauge how well you are
studying and learning in the course. Put everything away, set a timer for 45
minutes, and take it as if it were a real exam. Once you are done check the
answer key and tally your score. If you have questions on any of the
answers, please post on Piazza or come to office hours.
This exam contains 22 questions for 200 points total. Each question is
worth 9.1 points. Choose the best answer for each question. Good luck!

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Use the drawing of the molecule at the right to answer the following three questions.
1. What type of bond is the arrow pointing to?
A. Polar covalent bond
B. Non-polar covalent bond
C. Ionic bond
D. Hydrogen bond
Learning objective 2.1, 2.2: The arrow is pointing to a polar double
covalent bond between an oxygen atom and a carbon atom. The bond
is polar because oxygen is more electronegative than carbon.
2. What type(s) of functional groups are in this molecule?
A. Methyl only
B. Carbonyl only
C. Methyl and amino only
D. Methyl and carbonyl only
E. Methyl and carbonyl and amino
Learning objective 2.1, 3.1: This is thymine, one of the four bases in DNA. It has carbonyl groups
and methyl groups. See Table 4.9 for a review of functional groups.
3. How would you best describe this molecule?
A. Polar and hydrophilic
B. Polar and hydrophobic
C. Non-polar and hydrophilic
D. Non-polar and hydrophobic
Learning objective 2.1: Thymine has many polar covalent bonds, making it a polar molecule. Thus it
is also hydrophilic.
4. Which of the following figures displays a correct relationship about pH?
Learning objective 2.3, 7.1, 1.3, 2.4: pH is inversely proportional to hydrogen ion concentration (A).
pH is lower in lysosomes than in the cytoplasm (B), pH does not correlate with polar bonds (C), and
acids have lower pH than bases (D).
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5. Which of the following statements about carbohydrates, lipids, and proteins is TRUE?
A. Proteins are broken down to amino acids by dehydration reactions
B. Unsaturated fats contain one or more double bonds in their fatty acid tails
C. Monosaccharides always contain the atoms C, H, O, and N
D. Cellulose and glycogen are examples of disaccharides
E. A common feature of all lipids is that they are all hydrophilic
Learning objective 3.2, 3.3: Proteins are broken down via hydrolysis reactions, monosaccharides are
made of C, H, and O only (no N), cellulose and glycogen are polysaccharides, and all lipids are
hydrophobic. It is true unsaturated fats contain one or more double bonds in their fatty acid tails.
6. A mutation in a protein caused an alanine (A) amino acid to
be replaced with a glutamic acid (E) amino acid (their
structures are shown to the right). What effects do you think
the mutation will have on the protein’s function?
A. The mutation will not affect the protein’s function since both
the A and E amino acids are hydrophilic and thus the
structure will not be affected
B. The mutation will probably cause the protein to not function
correctly since mutations in proteins always negatively affect
protein function
C. Since E is hydrophilic and A is hydrophobic, the mutation will
disrupt the tertiary stucture and likely the function of the
protein
D. If the A amino acid is replaced by the basic E amino acid,
then the secondary and tertiary stuctures will be affected
and protein will likely not function correctly
Learning objective 2.1, 3.3: A (alanine) is hydrophobic and E
(glutamic acid) is acidic (and thus hydrophilic). If a hydrophilic amino
acid replaces a hydrophobic amino acid, it will “try” to be exposed
on the surface of the protein, which will likely affect the tertiary
structure and thus the function of the protein.
Antidepressants have been shown to affect diffusion of proteins in the plasma membrane,
which can lead to potential issues with cell signaling pathways. Use this information to
answer the following three questions.
7. The protein G5
a
spans the plasma membrane and is affected by antidepressants. G5
a
acts
in signal transduction to relay signals from outside the cell to inside the cell. What type of
protein is G5
a
?
A. Transmembrane protein
B. Peripheral protein
C. Motor protein
Learning objective 4.1: Since G5
a
spans the plasma membrane, it is a transmembrane protein.
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