MCB 2400 Study Guide - Final Guide: Robertsonian Translocation, Lethal Allele, Down Syndrome
10 Dec 2016
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Father of dna printing: monday september 10th 1984. Research: gene evolution in sparrows, repetitive sequences in human myoglobin gene. Found: human genome contains many regions of hypervariable dna, can serve as a unique identifier. Sequence polymorphism: (single nucleotide polymorphism, snp: agactagacatt, agattaggcatt. Length polymorphism:(short tandem repeat, str)(variable number tandem repeat, vntr: (cag)(cag)(cag, (cag)(cag) Snps: single base change in a region of dna. Strs:differences between persons occur in the numbers of repeats. Schematic of minisatellite and microsatellite (str) dna markers. Pcr primers are designed to target invariant flanking sequence regions. The number of tandem repeat units in the repeat regions. Dna-based method not only for biological identification, but also for sorting out family relationships. varies among individuals making them useful markers for human identification. Range from 2 to 10 bp repeat unit (bottom) (cid:498)within seconds it was obvious that we had stumbled upon a. Human genome contains many regions of hypervariable dna (vntr sequences)
