PSYO 2470 Chapter Notes - Chapter 12: Hyperalgesia, Nociceptor, Vasodilation
12 Feb 2018
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Nociceptors: the free branching and unmyelinated nerve endings that signal that the body tissue is being damaged or in danger to be damaged. *nociceptors are responsible for 2 sensation; pain, which is the feeling or perception of: irritation, stinging, aching and nociception, which is the process the provides the triggering to feel pain. Types of nociceptors: polymodal nociceptors: receptors that are sensitive to all stimuli, mechanoreceptors: they respond to strong pressure, thermal receptors: change on temperature, chemical receptors. Hyperalgesia: reduced threshold of pain/ increase sensitivity of painful stimuli/ spontaneous pain. Primary hyperalgesia: pain sensation on a past damaged tissue (that is already repaired). Secondary hyperalgesia: pain sensation around a past damaged tissue (that is already repaired). Inflammation: natural response of the bodies" tissue as it attempts to eliminate injury and stimulate the healing process. Bradykinin (chemical): depolarizes nociceptors, and make heat-activated ion channels to be more sensitive. Prostaglandins (chemical): increase sensitivity of nociceptors to other stimuli. (not pain)
