BIOLOGY 1A03 Chapter Notes - Chapter 4: Hydrophile, Dna Replication, Base Pair

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BIOLOGY 1A03 Full Course Notes
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BIOLOGY 1A03 Full Course Notes
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Nucleic acid is polymers made of monomer units of nucleotides. A nucleotide components- a phosphate group, a sugar, a nitrogenous base. Figure 4. 1- phosphate attached to carbon #5,nitrogen base attached to carbon # 1, and oh- group on carbon 3 to bond with next nucleotide. Nucleotides- ribonucleotide (sugar is ribose) and deoxyribonucleotide (sugar is deoxribose: deoxyribose is one less oxygen. In rna and dna, there will be unlinked 5" carbon while the other end has unlinked 3" end. Sequences of bases found in nucleotide always written in 5" to 3" direction because dna synthesized in this manner(bases added to 3" end of growing molecule. Polymerization of nucleotides is endergonic because addition of phosphate groups raises potential energy of substrate molecule enough to make reaction endergonic. Watson and crick proposed a secondary structure of dna that explained the following observation: chemists know structure of nucleotides and that dna polymerized though phosphodiester linkages.

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