BIOL 102 Chapter Notes - Chapter 17-18: Lac Operon, Rna Splicing, Archibald Garrod
7 Dec 2016
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The dna inherited by an organism leads to specific traits dictating the synthesis of proteins and of rna molecules involved in protein synthesis. Gene expression is the process by which dna directs the synthesis of proteins. Transcription: synthesis of rna from a dna template. Translation: synthesis of protein from an mrna template. Archibald garrod: suggested that genes dictate phenotypes through enzymes that catalase specific chemical reaction. He thought symptoms of disease reflect inability to synthesis certain enzyme. Beadle and tatum exposed bread mold to x rays creating mutants that were unable to survive on minimal media. Using minimal media and different pathway intermediates identification of 3 diff classes of mutants (each lacked an enzyme necessary to arginine synthesis. They developed: one gene- one enzyme hypothesis (each gene dictates production of. Many proteins are made of more than one polypeptides; and each polypeptide has it s own gene.
