BIOL 102 Lecture Notes - Lecture 11: Small Nuclear Rna, Sigma Factor, Structural Gene
7 Dec 2016
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Analysis of metabolic mutants revealed multiple enzymes that lead to arginine synthesis in a serial manner. Figure 12. 2 add different enzymes allow for different mutant: citrulline pathway of enzyme 1 and 2 to create wild-type and 2 other mutants. Different stages of loss of function could be identified, each associated with only one enzyme. One gene one enzyme hypothesis (1 gene coded for 1 unique enzyme) [beadle and tatum: single gene controlled the synthesis of a single enzyme. Transcription: production of mrna, occurs in nucleus of eukaryotes. Translation: production of proteins, occurs in cytoplasm of eukaryotes. Transcription and translation: occurs in the cytoplasm of prokaryotes. So prokaryotes can produce protein very quickly in response to the need for that protein: provides a mechanism to explain the very fast growth of prokaryotic cells. Flexible in gene expression change in environments very adaptable and very advanced able to produce proteins fast.
