PEDS101 Chapter Notes - Chapter 8: Neurotrophic Factors, Synaptic Vesicle, Schwann Cell

• School: University of Alberta
• Department: Physical Education and Sport
• Course: PEDS101
• Professor: Michael Kennedy

Document Summary

Synapse- a junction between a neuron and a target (pre and post synaptic cells) Myelin- insulates the axon (schwann cells), myelin wraps around the axon repeatedly, pushing the nucles of the schwann cell to the outside of the myelin sheath. The myelin consists of multiple layers of cell membrane. Schwann cells form myelin around a small segment of one axon. Nodes of ranvier- section of unmyelinated axon membrane between 2 schwann cells. An action potential is fired if the threshold level is reached. Moves organelles at rates of up to 400mm/day. Cell body: peptides synthesized and packaged, fast axonal trans. Along microtubule network (like a treadmill: vesicle contents are released by exocytosis, synaptic vesicle recycling, fast axonal transport back to cell body (retrograde, old components are digested in lysosomes. Describes the membrane potential that a single ion would produce if the membrane were permeable to only that ion.