KNES 437 Chapter Notes - Chapter 3: Single-Nucleotide Polymorphism, Childhood Obesity, Twin Study

• School: University of Calgary
• Department: Kinesiology
• Course: KNES 437
• Professor: Kelly Anne Erdman ,

Document Summary

Behavioral susceptibility to obesity: gene environment interplay in the development of weight. Introduction: obesity is one of the world"s great health challenges, contributing to chronic disease and premature mortality, and burdening health services. It is increasingly developing in childhood, and once developed, obesity is hard to reverse. The role of the environment in the development of obesity: environmental changes are widely agreed to account for the rapid in weight over the last 40 years. The genetic basis of obesity: research has established that genes play a major role in determining why people vary in weight, while all are exposed to the same obesogenic" environment. Gene-environment interaction phenomena i. e. individuals who are most genetically susceptible to the effects of the obesogenic" environment have gained the most weight. Genes load the gun, the environment pulls the trigger : appetite plays a causal role in the development of obesity, and appetite itself has a genetic basis.