BIOL 1090 Chapter Notes - Chapter 12: Nuclear Pore
18 Apr 2012
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Document Summary
Chapter 12 - the nucleus of a eukaryotic cell. Function : storage, replication and repair of genetic material, expression of genetic material (transcription, ribosome biosynthesis. Structure : nuclear envelope nuclear membrane, nuclear pores, nuclear lamina, nuclear contents genetic material (chromatin), nucleoplasm, nuclear matrix, nucleolus. Outer membrane binds ribosomes, continuous with the rough endoplasmic reticulum. Inner membrane has integral proteins that bind to the lamina. Inner membrane space continuous with the endoplasmic reticulum lumen. Separates nuclear contents from the cytoplasm (separates transcription and translation) Provides a selective barrier that allows for limited movement of molecules between the nucleus and cytoplasm. A thin meshwork of intermediate filaments bound to the inner membrane of the nuclear envelope by integral membrane proteins. Provides support for the nuclear envelope, as well as attachment sites for chromatin. Formed by the fusion of the inner and outer nuclear membrane. Fit into the nuclear pore and project into the nuceloplasm and cytoplasm.
