BIOM 3000 Chapter Notes - Chapter 2: Parathyroid Gland, Cholecalciferol, Hypocalcaemia

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Identify three hormones that mediate calcium homeostasis. Unit 2: endocrinology: calcitonin (from thyroid, parathyroid hormone (from this parathyroid, 1, 25-dihydroxyvitamin d3 (also called 1,25-dihydroxycholecalciferol, describe the effects of vitamin d on calcium absorption and indicate the cellular mechanism. Vitamin d is able to promote calcium absorption from the intestines by increasing a ca+2 atpase pump in the intestinal epithelial cells. This allows for calcium to enter into the epithelial cells, and the diffuse from these cells through the basolateral membrane into the bloodstream. Vitamin d can also increase renal reabsorption of calcium from urine as well as increase resorption of calcium from bone: identify and describe the steps in the formation of active vitamin d3 (1, 25- dihydroxycholecaliferol) Vitamin d3 is first produced from 7-dehydrocholesterol in the skin via actions of ultraviolet light. Vitamin d3 can also be taken in through diet. This vitamin d3 then enters the bloodstream and travels to the liver.

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