HSS 3305 Chapter 7: Neoplasia part 2
21 Feb 2019
School
Department
Course
Professor
Document Summary
Failure of immunologic defenses gene mutation in ell deregulates it causing abnormal proliferation: mutant cell produces cell glycolipids and glycoproteins not present in a normal cell. Immune sys recognizes them as abnormal and they are destroyed via cell-mediated and humoral mechanisms: tumor is a reflection of the failure of the body"s immune defenses, congenital deficiencies of immunologic defense mechanisms, decline of immune cells, Drugs and hormone preparations: factors leading to neoplastic transformation of cells virus, radiation, chemical carcinogens, unknown factors. Heredity and tumors predisposition results from multifactorial inheritance pattern. American cancer society warning signals: change in bowel/bladder habits or function, a sore that does not heal, unusual bleeding or discharge, thickening or lump in breast or elsewhere, obvious change in wart or mole, nagging cough or hoarseness. Early recognition of neoplasms: complete medical history and physical examination include special studies, rectum and colon; vagina using pap smear; esophagus and stomach, and x-rays to determine exact location of tumor.
