PSY290H5 Chapter Notes - Chapter 18: Butyrophenone, Serotonin Receptor Agonist, Twin
Document Summary
Chapter 18: biopsychology of psychiatric disorders: diagnosis of psychiatric disorders is difficult, guided by the dsm-iv-tr, difficulties: different symptoms are often caused by the same disorder, the same symptoms are often caused by different disorders. First antischizophrenic drugs: suggested to researchers that the two drugs act through the same mechanism as parkinson"s . Dopamine theory: striatums (caudates + putamens) of people dying of parkinson"s are depleted of dopamine, dopaminergic transmission disruption parkinson"s and antischizophrenic effects, early evidence of dopamine theory. Foods such as cheese, wine, pickles contain tyramine (bp elevator) Normally they don"t effect blood pressure too much though, because mao deals with the tyramine in the liver. But if people on mao inhibitors eat tyramine-rich foods, they run the risk of strokes due to surges in bp. Brain pathology: reductions in overall brain size, amygdala, medial prefrontal cortex, hippocampus are all affected. Implant bilateral anterior cingulate electrodes dbs effective in patients unresponsive to other lines of treatment.
