PSY333H5 Chapter Notes - Chapter 8: T Helper Cell, Innate Immune System, Inflammatory Bowel Disease

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Immune system basics immune system defends the body against infectious agents (ex. Viruses, bacteria, fungi, and parasites) immune defences brought by lymphocytes/monocytes (known as white blood cells collectively) two types of lymphocytes: t cells originate in bone marrow, migrate to thymus. Several kinds of t cells (t helper, t suppressor cells, cytotoxic killers, etc. : b cells - originate in bone marrow, mature in bone marrow. T/b cells attack infectious agents: t cells: cell-mediated immunity (page 141) When infectious agent invades the body, recognized by a macrophage (type of monocyte), and presents the foreign particle to a t helper cell. T cells begin to proliferate in response to the invasion. Results in activation and proliferation of cytotoxic killer cells which attack and destroy the infectious agent. T-cell component of the immune system is knocked out by aids virus: b cells: anti-body mediated immunity (page 142) Once macrophage t-helper cell collaboration occurred, t helper cells stimulate.

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