ANTC67H3 Chapter Notes - Chapter Van Dam et al. Article: Prospective Cohort Study, Cardiovascular Disease, Caffeine
ANTC67
Foundations in Epidemiology
Page ! of !1 2
COFFEE, CAFFEINE & RISK OF TYPE 2 DIABETES: A PROSPECTIVE COHORT
STUDY IN YOUNGER AND MIDDLE-AGED U.S WOMEN — Van Dam et al.
Objective
-high habitual coffee consumption has been associated with a lower risk of type 2 diabetes
-data on lower levels of consumption is sparse
Research Design and Methods
-prospective cohort study
-88, 259 U.S women aged 26-46 years without history of diabetes at baseline
-consumption of coffee and other caffeine containing foods and drinks was assessed in 1991,
1995 and 1999
-documented 1,263 incident cases of confirmed type 2 diabetes
-biennailmailed questionnaires
-follow up began at the return of the 1991 questionnaire
-excluded women that didn't complete a dietary questionnaire, had a history of diabetes or a
cardiovascular disease at baseline
-participants asked how often on average during the previous year they had consumed
caffeinated and decaffeinated coffee, tea, different types of caffeinated soft drinks and
chocolate products
-asked about the usual method of preparing coffee
Assessment of Type 2 Diabetes
-women who reported a diagnosis of diabetes on a biennial follow up questionnaire were sent a
supplementary questionnaire asking about diagnosis and treatment of diabetes and history of
ketoacidosis
-confirmation of diabetes required at least one of the set criteria plus at least one classic
symptom
Assessment of Medical History, Anthropometry and Lifestyle
-information about age, weight and height, smoking status, physical activity, history of diabetes
in first degree relatives, use of postmenopausal hormone therapy, use of oral contraceptives
and personal history of diabetes, cardiovascular diseases and cancers
-this information was updated every 2 years
Statistical Analysis
-person-years of exposure calculated from the date of return of the baseline questionnaire to the
date of diagnosis of type 2 diabetes, death or 1 July 2001 (whichever came first)
Results
-relative risk: !
- 0.87 for 1 cup of coffee!
find more resources at oneclass.com
find more resources at oneclass.com
Document Summary
Coffee, caffeine & risk of type 2 diabetes: a prospective cohort. Study in younger and middle-aged u. s women van dam et al. High habitual coffee consumption has been associated with a lower risk of type 2 diabetes. Data on lower levels of consumption is sparse. 88, 259 u. s women aged 26-46 years without history of diabetes at baseline. Consumption of coffee and other caffeine containing foods and drinks was assessed in 1991, Documented 1,263 incident cases of confirmed type 2 diabetes. Follow up began at the return of the 1991 questionnaire. Excluded women that didn"t complete a dietary questionnaire, had a history of diabetes or a cardiovascular disease at baseline. Participants asked how often on average during the previous year they had consumed caffeinated and decaffeinated coffee, tea, different types of caffeinated soft drinks and chocolate products. Asked about the usual method of preparing coffee.
