ANTC67H3 Chapter Notes - Chapter 9 (sections 9.1-9.3.2 & 9.4): Survivorship Bias, Cohort Study, Recall Bias

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9 Oct 2016
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Case control studies allow the evaluation of a wide range of exposures that might relate to a specific disease. Look at a wide range of exposures and can be conducted relatively cheap and quickly. Results from exploratory case control studies may suggest specific hypotheses which can be tested in specifically designed studies. Precise criteria for the definition of a case is essential. Objective evidence that the cases really suffer from the disease or condition of interest. Sometimes impossible to eliminate all cases whose diagnosis is not properly documented. Case definition should be defined in a way in which there is no ambiguity about types of cases and stages of disease to be included in (validity more important here than generalizability) By ensuring that cases are a relatively homogenous group, we maximize the chances of detecting important etiological relationships. Generalizability is less important than establishing an etiological relationship.

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