PSYC62H3 Chapter Notes - Chapter 10: Prodynorphin, Hydromorphone, Antisocial Personality Disorder
Document Summary
Opiods: psychoactive substances that elicit pharmacological effects by acting on opioid receptors: most effective pain-relieving meds and most sought-after substances for abuse. Laudanum: an opium-containing drink intended for medical purposes: 19th century, drug stores legally sold opium products such as morphine, various elixirs produced, beginning of the 20th century marks the religious and political movements leading up to the. Opioid drug interactions with the endogenous opioid system: endogenous opioid system includes opioid neurotransmitters and receptors, endogenous opioids are neuropeptide neurotransmitters. Propetide: chain of amino acids containing one or more peptides: cleavage refers to the separation of a peptide segment from a longer propeptide, endogenous opioid neuropeptides consist of -endorphin, metenkephalin, leu-enkephalin, dynorphin. Opioid drugs: classification by receptor action: most of the opioid drugs used, either recreationally or instrumentally, act on opioid receptors, drugs can have different effects at the receptors, opioid characterized by their receptor actions.
