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Canada (161,538)
Psychology (9,695)
PSYB65H3 (479)
Chapter 27

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Zachariah Campbell

CHAPTER 27 Schizophrenia Structural Abnormalities Although the results are variable most researchers agree that schizophrenic brains weigh less than normal brains and that the ventricles are enlargedSchizophrenics have also been suggested to have smaller frontal lobes or at least a reduction in the number of neurons in the prefrontal cortex Studies of cellular structure have shown abnormalities in both the prefrontal cortex and the hippocampus Bichemical Abnormalities in the Schizophrenic Brain Important pathway in prefrontal cortexdopaminergic pathway from the tegmental area Interference with this disrupts cognitive tasks in lab animalsAntipsychotic drugs AKA neuroleptic drugs principally affect psychomotor activity They work on the dopamine system A person can induce schizophrenic symptoms if they take drugs like cocaine amphetamine Ldopa which have dopamine componentsOther chemical abnormalities have been found in patients with schizophrenia Mood Disorders Clinical depression mania bipolar disorder Neurochemical Aspects of Mood Disorders Depressed patients given a certain drug were found to have their monoamines supply depletedthese include serotonin dopamine and norepinephrine Lead to idea that depletion of monoamines contributed to depression
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