PSYC62H3 Chapter Notes - Chapter 4: Endocrine Disruptor, Nmda Receptor, Nicotine
Document Summary
Do environment stimuli contribute to heroin tolerance: sheppard seigel suggested that condition changes may partly account for heroin overdose in experienced users. It is important for drugs to reach the site of action but designing drugs to pass through the body is not easy: there are 4 primary stages of a drug"s pharmacokinetic properties: absorption, Absorption: process of absorption refers to the entry of drug into circulatory system, before entering into the circulatory system, the drug must diffuse through different membranes and into organs. Most drug absorption occurs in the small intestine. Orally administered drugs must be encased within a tablet or capsule to protect it from digestive acids in the stomach. At the same time, much of the tablet or capsule must be dissolved by the digestive acids to free drug molecules for absorption. Analgesic (pain-relieving) drug tylenol takes 30min: table 4. 1 covers other routes of administration.
