Chapter all: Principles of Cell Signaling

• School: UTSG
• Department: Biology
• Course: BIO120H1
• Professor: all

Document Summary

Principles of cell signaling: cell signaling in unicellular organisms. Quorum sensing the process by which bacteria secrete chemical signals to which the neighboring cells respond by accumulating at greater population density allowing coordination of different behaviors like motility, spore formation, sexual conjugation and antibiotic production. Eg: secretion of mating factor (peptide) by saccharomyces cerevisiae: cell signaling in multicellular organisms - extracellular signal molecules mediates communication between cells (intercellular signaling, 4 types of intercellular signaling. Endocrine: cell surface receptor present on target cell, binds the signal molecule and initiates a response in the target cell, types of cell surface receptors: Ion-channel-coupled receptors or transmitter-gated ion channels or ionotropic receptors. Intracellular signaling - chain of intracellular signaling events that are responsible for modifying the behavior of the cell according to the signals received by the cell-surface receptors: 2 types of intracellular signaling molecules. Water soluble cyclic amp, ca2+ lipid soluble diacylglycerol.