BIO130H1 Chapter 4: Chromosomes and Chromatin
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BIO130H1 Full Course Notes
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Document Summary
Chromosomes appear in the beginning of mitosis. And disappear one again after cell division has ended. Packaging of dna is important it allows it to stay maintained in the nucleus while still performing its function. Chromosome that are composed of dna and associated with proteins are called chromatin. The centre of the chromosome holding chromatics together is called the centromere. The end of the chromosomes are areas called telomeres. the orderly packaging of dna depends on histones, a group of small proteins the posses an unusually high content of the basic amino acids arginine and lysine. Arginine and lysine are positively charged molecules so they are important in the neutralization of the negatively charged backbone of the dna keep it connected. The dna strands coil around the histones and repeated structures like this in a chain is called nucleosomes nucleosomes contain dna wrapped around a core particle( consisting of.
