BIO130H1 Chapter Notes - Chapter 2: Nitrogenous Base, Alpha And Beta Carbon, Alpha Helix

• School: UTSG
• Department: Biology
• Course: BIO130H1
• Professor: Melody Neumann

Document Summary

Readings - 77-79 (from last week); 393-397; 33-42 (chemistry review); 50-63; 70-72. Readings: 411-414; 400-406 (skip human perspectives and focus on complexity of eukaryotic genomes section) Nucleotide: the basic building blocks of dna. Phosphate attached to 5" and nitrogen base attached to 1". The nucleotides are covalently linked to one another. A nucleotide has a polarized structure: 5" to 3". Chargaff: determine the relative amounts of each base in various samples of dna -- base composition. The ratio of the bases varies from sample to sample. The watson-crick proposal two chains of nucleotides the two chains spiral around each other to form a pair of right-handed helices. the two chains run in opposite direction -- antiparallel. Must contain the information for the specific order of amino acids in all. The information in dna must be used to direct the order. Dna breaks as a zipper, serve as a template directing the order.