IMM250H1 Chapter Notes - Chapter 1-8: Death Domain, Immunodeficiency, Lectin Pathway

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22 Aug 2018
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Commensal microbes - our microbiome , vastly colonize us and perform important metabolic and protective functions for us. Function of the immune system is to promptly detect presence of pathogens and react with a response tailored to the particular type of assault. Divided into two types of responses: innate immunity and adaptive immunity. Innate immunity is the first line of defense against infectious agents. Makes rapid responses that may eradicate the infection at an early stage. Later, adaptive responses may be generated if infectious agent is not killed. Lead to state of resistance to reinfection, called immunological memory. From the rise of the concept of immunity to variolation. The word immune derives from latin term immunitas that means (cid:548)to be exempt from(cid:549) Referred to in ancient rome as being exempt from public duties or institutions. Concept of immunity from illness precedes the use of immunitas as a legal term.

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