Biochemistry 2280A Chapter Notes - Chapter 20: Tumor Suppressor Gene, Benign Tumor, Cell Cycle Checkpoint
24 Dec 2016
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Cells divide when they are needed and kill itself when not. One bad cell is not bad but one bad cell causing other cells to be bad is bad lol. Two heritable properties: proliferate in defiance of normal constraints, invade and colonize territories normally reserved for other cells. If not invasive: will proliferate but cluster as a single mass: called a benign tumour. Malignant tumours invade from primary tumour and enter bloodstream, lymphatic vessels to spread and cause secondary tumours: metastases. No causes of cancer but some things related: e. g. high levels of cervical cancer (in the cervix of the uterus) correlated with sexual. Experience : now correlated with hpv which is transmitted through intercourse, can accidentally cause proliferation of infected cells, implement vaccines for hpv to lower levels of cancer. Arises from pathological changes in info carried by dna.
