Biology 2581B Chapter Notes - Chapter 13 + David Smith Article: Steal My Sunshine, Horizontal Gene Transfer, Gene Regulatory Network
4 Jun 2017
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Branches rejoining: like a web organisms can undergo lateral gene transfer. Apicomplexans causes many diseases has a remnant chloroplast called a apicoplast. Ipp produced by apicoplast is required for the apicomplexan parasite survival: enough (when supplied synthetically) can result in induced loss of organelle. Chloroplasts can make: fatty acids and isoprenoid precursors. Fatty acids: if we mess around and take away in liver of plasmodium and toxoplasma but parasite survives in rbc can get fatty acids from host. Isoprenoids: derived from 5 carbon ipp and isomer dmapp: animals and fungi use mevalonate pathway while plants and bacteria use the doxp pathway. Good to study live attenuated viruses plastidless viruses. Horizontal gene transfer a hallmark of animal genome: Non animal sequences horizontally transferred: fat and obesity associated gene horizontally acquired, genes eventually get introns domesticated over time, hgt probably happened earlier in mammals, some species more susceptible.
