Biology 1001A Chapter Notes - Chapter 12.2: Thymine, Purine, Base Pair

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9 Nov 2016
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Watson and crick discovered the structure of dna in 1953. 12. 2a watson and crick brought together information from several sources to work out. Before watson and crick, it was established that dna contains 4 different nucleotides. Each nucleotide is made up of the five-carbon sugar deoxyribose (where the carbon atoms are numbered 1" to 5"), a phosphate group and one four nitrogenous bases: adenine, guanine, thymine, and cytosine. A and g are purines => nitrogen bases built from a pair of fused rings of carbon and nitrogen atoms. T and c are pyrimidines => built from a single carbon ring. A always pairs with t, and g always pairs with c => chargaff"s rule (a and t form 2 hydrogen bonds; g and c form 3 hydrogen bonds) Nucleotides form a polynucleotide chain where the deoxyribose sugars are linked by phosphate groups in alternating sugar-phosphate-sugar-phosphate to form a sugar- phosphate backbone.

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