Biology 1001A Chapter Notes - Chapter 26: Copy-Number Variation, Sister Chromatids, Synaptonemal Complex
Document Summary
Mechanism of recombination during prophase: cut one strand from each chromosome and reattach their ends by switching them, cut the other strand and do the same. In total 4 strands are cut and reattached. How homologues pair in order for all non-sister chromatids to participate in recombination: homologues pair one on top of the other, all non-sister chromatids are touching and can recombine. Mechanism by which recombination creates new combinations of alleles: only specific sections of a chromatid"s genome crosses over with another chromatid, this creates random combinations of alleles that are passed down to daughter cells. Mechanism by which recombination creates copy number variation (cnv: slippage can result in unequal crossing over; one chromosome has too many genes and the other has too few. Changes in c and n during meiosis: premiotic interphase: 2n, 4c up until anaphase i, telophase i: 1n, 2c up until anaphase ii, telophase ii: 1n, 1c.
