Biology 1201A Chapter Notes - Chapter 12: Efficiency Movement, Ion, Ribonucleoside

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5" end - the end of a polynucleotide chain at which a phosphate group is bound to the 5 carbon of a deoxyribose sugar. 3" end - the end of a polynucleotide chain at which a hydroxyl group is added to the 3 carbon of a deoxyribose sugar. Dna polymerase iii - the main, general purpose polymerase for replicating dna. Dna polymerase i - a specialized polymerase responsible for removing rna primers and replacing them with dna. Dna ligase - in dna replication, an enzyme that seals the nicks left after rna primers are replaced with dna replication bubble - a structure resulting from bidirectional dna replication from a given origin. Dna repair mechanism - mechanisms to correct base-pair mismatches that escape proofreading mismatch repair - repair system that removes mismatched bases from newly synthesized dna strands mutations - a spontaneous and heritable change in dna. Two significant problems of dna: dna damage and contamination.

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