PS282 Chapter Notes - Chapter 12: Hypericum Perforatum, Natural Health Product, Tricyclic Antidepressant
Document Summary
O health canada is responsible for establishing standards for the safety and quality of all foods and drugs sold in this country: fda (food and drugs act) According to fda any substance manufactured, sold or represented for use in the diagnosis, treatment, mitigation or prevention of a disease, disorder or abnormal physical state, r its symptoms, in human beings or animal is a drug. To relieve restlessness or nervousness and to help treat symptoms of sleep disorders demons: limited evidence of effectiveness, hypericum extracts are, st john"s wort. Superior to placebo in patients with major depression. Have fewer side effects than standard antidepressants. Was sold in chocolate, mint, butterscotch and caramel flavors. In 80"s people began expressing concern about the safety of products containing ppa. Ppa shown to increase blood pressure, increased risk of hemorrhagic stroke in women shut down by 2001: misused drug for weight loss, ephedra (ma huang)
