BIOL 3051 Chapter Notes - Chapter 2.1: Pernicious Anemia, Serum Iron, Bleeding On Probing
20 Apr 2020
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Acute/chronic anemia: tissue iron requirements are increased during: growth, menstruation, pregnancy, blood donations, pathological bleeding (peptic ulcers, hemorrhoids, bleeding gums, intestinal disease, hookworm infestation, chronic hemodialysis, hypochromia rbcs have less color. Results in loss of rbcs with iron staying in body. Results in reduced survival or rbcs: low tissue iron stores few rbcs & paler/smaller hypochromic/microcytic (less hb content) Acute vs chronic anemia: acute anemia is when there"s an abrupt drop in rbcs. Due to hemolysis or hemorrhage: chronic anemia is gradual decline in rbcs. Causes include iron, nutritional deficiencies, chronic disease, drug induced. Cause of iron deficiency, dietary: 56% of women in developing counties have serum ferritin levels <8ug/l & hb levels. This results in preterm birth, impaired mental & motor development among children: phytates (foracinm 2% of cereals, nuts, legumes), polyphenols in teas, vegetables, phytic acid in soybeans.
