PSY-B - Psychology PSY-B 320 Chapter Notes - Chapter 5.2,5.4: Central Nervous System, Autonomic Nervous System, Serotonergic

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Chapter 5
Neurotransmitter Systems and Behavior
A single neuron may use one transmitter at one synapse and a different transmitter at
another synapse
Different transmitters may coexist in the same terminal or synapse
Caution against the assumption of a simple cause-and-effect relation between a
eurotrasitter ad a behavior….but…
Four Activating Systems in the Central Nervous System
Activating System
Neural pathways that coordinate brain activity through a single neurotransmitter
Cell bodies are located in a nucleus in the brainstem and their axons are
distributed through a wide region of the brain
Four Systems
Cholinergic, Dopaminergic, Noradrenergic, and Serotonergic
The Central Nervous System: Mediating Behavior
Systems in the Central Nervous System
Cholinergic System (Ach)
Involved in normal waking behavior and is thought to function in attention and
memory
Loss of holiergi euros assoiated ith Alzheier’s disease
Dopaminergic System (DA)
1) Nigrostriatal path involved in coordinating movement; degeerates i Parkiso’s disease
2) Mesolimbic path enhances responses to environmental stimuli; implicated in addiction and
schizophrenia
Noradrenergic System (NE)
Imbalances associated with depression or mania
Plays a role in learning by stimulating neurons to change their structure
Serotonergic System (5HT)
Plays a role in wakefulness and learning
Imbalances associated with depression, schizophrenia, obsessive-compulsive
disorder, sleep apnea
Neurotransmission in the Somatic Nervous System
Cholinergic Neuron
Neuron that uses acetylcholine (ACh) as its main neurotransmitter
Excites skeletal muscles to cause contractions
Nicotinic ACh Receptor
When ACh (or nicotine) binds to this receptor, its pore opens to permit ion flow,
thus depolarizing the muscle fiber
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