BISC300 Chapter Notes - Chapter 15: Telomerase Reverse Transcriptase, Tata Box, Small Nuclear Rna
27 Nov 2016
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Why consider eukayotic and archaeal genetics together: archaeal machinery for genetic information processing is more similar to that of eukaryotes than of bacteria. 15. 2 dna replication: similar overall, but w/ diff replisome proteins: dna replication is similar in all cellular organisms. It is accomplished by a huge complex of many different proteins called the replisome. Dna of most bacteria is circular and replication begins at a single origin of replication. Bacterial replicative dna polymerase (dna polymerase iii) is recruited to the origin only after the initiator protein dnaa begins assembly of the bacterial replisome, which is composed of at least 30 proteins. The replication forks move bidirectionally from the origin until the entire circular chromosome is replicated: dna replication in eukaryotes. Major features of eukaryotic genome structure relevant to dna replication include having multiple chromosomes, each of which is usually much larger than a typical bacterial chromosome.
