GEOG103 Chapter Notes - Chapter 13-15: Lifesaving, Duffy Antigen System, Plasmodium Falciparum
6 Mar 2018
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Document Summary
Main driver for development of antibiotic resistance world wide. Daily dose- assumed average maintenance dose per day for a drug used for its main indication in adults. More exposure bacteria have to antibiotic more likely the strain resistant to that antibiotic will arise and spread. Drug pressure are multifactorial: resistance causes are ecological, epidemiological, sociocultural, and economic, little incentive for companies to develop new classes of antibiotics (greater risk and expense) Several nordic european countries have lower outpatient antibiotic consumption compared to mainly southern/eastern european countries. Lower antibiotic use have lower antibiotic resistance levels. Hospital antibiotic consumption 10-fold lower than that used in ambulatory care. Antimicrobial resistance problem particularly pressing in developing countries (infectious disease burden is high; cost constrains old antibiotics) Antibiotics are also used in agriculture emergence of human pathogens that are resistant to common antibiotics. Goal- use only in people w/ bacterial infections that need to be cured by antibiotics.
