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BCHM 3P01 (21)
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BCHM 3P01 Feb 6.docx

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Department
Biochemistry
Course
BCHM 3P01
Professor
Nicholas D Vesprini
Semester
Winter

Description
BCHM 3P01 Glycolysis and FermentationChapters 1617February0614802 AMBreak glucose into pyruvate used in the citric acid cycle main goal of glycolysis Free Energy Change and Spontaneous Exergonic Reactions ABCDPutting in a lot of ATP to synthesize glucose The free ATP given off in the reaction is used to drive another reaction This is coupling Overview of Glycolysis Aka as EmbdenMeyerhofParnas pathway Glycolysis existed before photosynthesis or O2 production therefore it existed before respiration no need for O2 in reactions Glucose C6 is catabolized to two molecules of pyruvate C3 via fructose 16 biphosphatePyruvate has lower free energy than glucoseEnergy released from glucose oxidation is used to synthesize 2 mol of ATPmol glucose 2 mol of NAD reduced to 2 NADPHmol glucose Overall 10 steps in the pathway For glycolysis to continue NAD must be regeneratedHOW oUnder anaerobic contions via alcohol yeast or homolactic muscle fermentation
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