BCHM 3P01 Lecture Notes - Acetyl-Coa, Futile Cycle, Pyruvic Acid

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Outline: introduction, free energy, free energy and standard free energy, energy coupling, coupled reactions, thermodynamics of glycolysis. Ab is unstable and high energy, shown by an increase in energy level. The magnitude of the increase is known as the energy of activation (ea) and acts as a barrier to prevent the production of c. The higher ea is the less likely it will be for a & b to form a transition state and successfully be converted to c. Ea is the rate limiting step in the reaction, the larger its value the slower the. Therefore plays a role in the rate of reaction. How much energy was conserved and in what form? o. When pyruvate is converted to acetyl coa energy is conserved through. The first set of questions are thermodynamics and the second set of questions are kinetic questions. As a & b collide a transition molecule (ab) will be formed very briefly before c is.

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