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Lecture 14

BIOL 1F25 Lecture Notes - Lecture 14: Weight Loss, Cardiac Arrest, Lysine


Department
Biological Sciences
Course Code
BIOL 1F25
Professor
Gaynor E Spencer
Lecture
14

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BIOL 1F25
NOV 4TH 2015
LEC 14
Cocaine
Derived by coca bush
Grown in Peru Bolivia and Columbia
Starts as a leaf then made into a coca base
CNS stimulant
oRegulated as a narcotic but its not
oStimulates release of brain chemicals that play a role in mental alertness
and excitation
o“One of the most powerful pharmacological reineforcers known. O7nce…
Experienced, tendency to reuse is nearly irresistible “
Exhilaration and euphoria
Heightened alertness
Greater capability for work
Less fatigue
Less need for food and sleep
“Perfect illusion “ drug: ego food!
3 forms
Hydrochloride salt
oWhite powder
oWater soluble
oSniffed or taken intravenously
Street dealers often dilute with cornstarch
History of cocaine production
1st isolated by German chemist: Friedrich Gaedcke in 1855: “erythroxyline”
Purified by Albert Niemann in 1859: “cocaine”
Discovered cocaine acts as a local anesthetic
Eye, nose and throat surgery
(1 oz enough to perform 28 nose jobs)
Sigmund Freud
Lrg role in western cocaine industry
Cocaine pharmacotherapy
Digestive disorders
Cure for depression
Aphrodisiac
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