BIOL 1F25 Lecture Notes - Lecture 7: Motor Neuron Disease, Superoxide Dismutase, Superoxide
25 Feb 2016
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Recall: no family history) with als; inherited) fals: developing als. Up to 90% of als cases are sporadic (sals: no known cause, Up to 10% of als cases are familial (fals: close family relative. Child of patient with inheritable als has 50% chance of. Of chromosomes are from father other are from mother. Physical characteristics/appearance= phenotype : can depend on combination of genetic & environmental factors. Examples of heritable human traits: eye colour (blue, brown, curly hair, tongue rolling, blood type. Diff. variants of a trait (ex. brown eyes vs. blue eyes) are caused by diff. variants of genes: allele= variant form of a gene, ex. one allele causes brown eyes, another allele causes blue eyes. Some alleles are dominant- can mask other alleles. Other alleles are recessive- are masked by dominant alleles. Each person gets one set of alleles from father (sperm) and one set from mother (egg)
