BIOL 3P30 Lecture Notes - Lecture 6: Phosphorylase Kinase, Muscle Contraction, Glycogen
22 Aug 2015
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Pyruvate dehydrogenase o to glycolysis in o mitochondrial membrane. If this enzyme is inhibited o pyruvate cannot be oxidized and therefore turns into lactic acid o. Co2,nadh, h+, and acetyl-coa o is when it is working. If not it oxidizes and turns into inner the present to balance. No need to oxidize pyruvate if there is lots of it in the system. Exist in phosphorylated state which is turned off or not phosphorylated which. Regulation of protein kinases camp regulation of pka (in. Small molecules and o interact to turn the kinases on or off. Stored in the sarcoplasmic reticulum or the endoplasmic reticulum. Largest family of receptors on cell surface (>1000 members) Epinephrine (adrenergic) receptor each of , , subunits. Increase diversity of response: lateral mobility important proteins. E1, 2, and 3 are effectors (being affected by the g- protein) Epinephrine controls glycogen breakdown in times of high stress/danger.
