BIOL 3P30 Lecture Notes - Lecture 7: Phosphorylation, Atp Synthase, Weight Loss

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Weight loss drug: collapses the gradient so that the mitochondria needs to. Proton leak also controls metabolic rate o work harder therefore metabolic rate. Both of the above control about 70% of metabolic rate. Using energy in chemical bonds of fuels to synthesize atp fro adp and pi. The fermentation in fermentation is not producing enough atp per unit time. Breathing in more oxygen only raises a little more because it"s not in demand at rest, for example consumption work. Animal cells use 3 major metabolic fuels: carbohydrates (glucose), lipids (fatty acids), proteins (amino acids) These metabolic fuels are imported into the mitochondria and enter the tca cycle as acetyl-coa (usually) From beta-oxidation of fatty acids, glycolytic pyruvate, and catabolism of some amino acids. What mitochondria actually look like: the structure of the cristae tubules based on electron microscopic tomography. Note: inside of cristae tubules continuous with intermembrane space.

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