BIOL 2020 Lecture Notes - Lecture 14: Intermediate Filament, Cytoskeleton, Microfilament

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Biol2020: section 5 cytoskeleton and cell motility. General features: cytoskeletal elements are not membrane bound. All cytoskeletal elements are polymers made up of individual monomer units that link together to form one long structure: microtubules = polymers of tubulin, microfilaments = polymers of actin. There is a whole bunch of proteins that can join together to form intermediate filaments. It is a fairly weak linkage, which leads to the fact that they are all dynamic elements constantly growing and changing at a very fast rate. Generally speaking, every single function of cytoskeleton boils down to being structural or something to do with movement they can either be moving things around inside of the cell, or the entire cell. Microtubules: largest fibers (25 nm diameter, hollow tubes made of tubulin proteins. Microtubules are huge if you think of the width of a membrane (5-10nm), microtubules are double-triple in width.

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