MICI 3119 Lecture Notes - Lecture 19: Endospore, Plant Pathology, Permease
21 Oct 2018
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Inverted develops when inside is more positive than outside. Evidence of k+ uptake helps e. coli to achieve ph homeostasis: k+ was added at 10 minutes. Na+/h+ antiporter: ph homeostasis is maintained by a na+/h+ antiporter. Primary transport: oxidation-reduction reactions (etc, atp-dependent ion translocation, osmotic shock-sensitive transport systems, sugars uptake by the phosphotransferase (pts) system. Atp-driven cu2+ efflux: copper is an essential element for growth as a cofactor for enzymes, copper is very toxic to cells. Iron is an essential element for bacteria, serving as a cofactor for many enzymes and redox centre in cytochromes and iron-sulfur proteins: free iron is inaccessible to bacteria in the natural environment. Siderophores: siderophores are amongst the strongest soluble fe3+ binding agents known. In mammalian hosts, free iron is in the order of 10- 24 m, because iron is tightly bound to proteins such as hemoglobin, transferrin, lactoferrin and ferritin (i. e. inaccessible).
