PSYO 1011 Lecture Notes - Lecture 7: Reuptake, Cerebellum, Immune System

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3 ways drugs can influence neural activity: Act on presynaptic neuron to increase or decrease neurotransmitter release. Act in the synapse (synaptic cleft) to increase or decrease the process that remove the neurotransmitter from the synapse. Binds to the postsynaptic cell increasing or decreasing its activity. Lsd: activates some types of serotonin receptors. Amphetamines: inhibits reuptake of dopamine and other neurotransmitters. Less able to fire activity in the brain (blockage) Neurotoxin (can be fatal if intake too much) They are secreted by the endocrine gland. Bind to receptors on the neuron, altering neural activity. Some hormones (i. e. testosterone and estrogen aka steroids) bind to receptors inside neuron. Can change number of chemicals and/or amount of neurotransmitter produced. Produced by the testes and adrenal glands. Levels of testosterone in the blood of rate correlates w/ their aggressiveness. Castrated male rats tend to be less aggressive (removing sources of testosterone) Injecting testosterone into catered rats reinstated their fighting behaviour.

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