BIOL 271 Lecture Notes - Bone Marrow, Thymus, Thoracic Duct

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9 Mar 2014
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Lymphatic System
Lymphatic Circulation
organs, vessels and a fluid called lymph
similar to interstitial fluid
colourless fluid with WBCs
Organs
red bone marrow
thymus
spleen
lymph nodes
diffuse lymphatic tissue
tonsils, adenoids, Peyer's patches
Functions
drains excess interstitial fluid and plasma proteins from tissue
spaces
transports dietary lipids and lipid-soluble vitamins from GI tract
to the blood
facilitates immune responses
recognizes and destroys microbes, toxins and abnormal
cells by:
direct attack (T-cells)
secretion of Ab (B-cells & T-cells)
Lymphatic Capillaries
closed-ended tubes in spaces between cells
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found in all tissues except:
avascular tissue (cartilage, epidermis, cornea)
portions of spleen, red bone marrow
tissue fluid enters through spaces between endothelial cells
when interstitial pressure is high
anchoring filaments prevent tube from collapsing under outside
pressure
Lacteals
specialized lymphatic capillaries in villi of small intestine
absorb dietary lipids (creamy-white lymph called chyle)
large nutrients cannot enter the cell except by specialized
lymphatic capillaries
Lymphatic Vessels and Circulation
lymphatic capillaries combine to form lymphatic vessels
resemble veins with thin walls, more valves
flow through lymph nodes
form plexuses (networks) around viscera
lymph trunks:
L. jugular trunk
L. subclavian trunk
L. lumbar trunk
intestinal trunk
vessels unite to form _______
lymph ducts:
R. lymphatic duct
drains lymph from R side of head and chest, and R arm
to R subclavian v.
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