BIOL 112 Lecture Notes - Lecture 8: Nuclear Membrane, Nuclear Lamina, Endomembrane System

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BIOL 112 Full Course Notes
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BIOL 112 Full Course Notes
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Transport happens via diffusion, diffusion does not function over large distances. Movement in random directions rather than straight paths. No nuclear envelope, few or no organelles, very small. Dna transcription to rrna/ mrna by rna polymerases rrna is not translated, it directly folds into 3d structures. Ribosomes are comprised of 4 rrnas and 80 proteins in the nucleolus (substructure of nucleus) Membrane proteins are made in rough er. Ribosomes are attached on outside of rough er. There are free ribosomes within the cytoplasm of a cell. Signal hypothesis: signal sequence synthesized, signal binds to srp (signal recognition particle, srp binds to receptor, protein synthesized into er, protein synthesis complete. Bind to receptor, endosome forms around it (engulfing), processed, digestive enzymes receive endosome, lysosome forms. Detected, phagosome formed, delivered to lysosome, digested, particles released to cytosol. Damaged organelle surrounded by membrane, delivered to lysosome, recycled.

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